On the night of July 21, the IDF continued operations in the Gaza Strip. Information on the night's combat activities came exclusively from sources in Gaza.

Last night, the IDF targeted sites in the northern, central, and southern parts of the Gaza Strip. According to available data, the intensity of the combat was lower than the previous night. In the north of the Gaza Strip, IDF artillery and air forces struck targets in the southeast of the Zeitoun area, on the southern outskirts of Gaza City. In the center of the Gaza Strip, IDF artillery shelled targets in Al-Bureij. In the south of the Gaza Strip, sources in Gaza reported an explosion in the western part of Rafah.

The IDF has not yet commented on the combat activities in Gaza on July 21. However, the IDF reported that on Saturday, July 20, a soldier from the 52nd Battalion of the 401st Brigade "Iron Tracks" was seriously wounded in combat in the southern Gaza Strip. The wounded soldier was transported to the hospital.

The Hamas-run ministry of health claims that over the past day, more than 60 people were killed in Gaza by IDF strikes. Specific reports include at least 11 killed in an IDF strike on two houses in Nuseirat, in the center of the Strip, and at least seven killed in an IDF strike on the Khalifa family's home in Al-Bureij, in the center of the Strip.

Another "journalist" was reportedly killed in a strike on a house in Nuseirat, with indications that this journalist was the intended target as no other casualties were reported. In addition, at least 20 were killed and dozens injured in an IDF strike on a target in eastern Khan Younis, in the south of the Strip.